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Ferrocene-containing tetrahydropyrazolopyrazolones: Antioxidant and antimicrobial activity
(Journal of Inorganic Biochemistry, 2018-12)
A series of ferrocenes which contain dinitrogen-fused pyrazolidinone ring were synthesized from acryloylferrocene (4) and N,N′‑cyclic azomethine imines (3). Novel 5‑aryl‑6‑ferrocenoyltetrahydropyrazolo[1,2‑a]pyrazol‑1(5H)-ones ...
Design and synthesis of novel ferrocene-quinoline conjugates and evaluation of their electrochemical and antiplasmodium properties
(European Journal of Medicinal Chemistry, 2020-02)
The tropical disease malaria is responsible for more than 400,000 deaths annually, especially in Southeast Asia and Africa. Although the number of malaria cases is declining, there still is an urgent need for novel ...
Synthesis, structural and electrochemical characterization of novel 1,3-ketoureas bearing a ferrocenyl group
(Polyhedron, 2018-02)
Twenty-two novel 1,3-ketourea derivatives bearing ferrocene moiety were synthesized in good-to-excellent yields (up to 99%) via simple and efficient protocol. This solvent- and catalyst-free synthesis was achieved by ...
Acryloylferrocene as a convenient precursor of tetrahydropyrazolopyrazolones: [3+2] cycloaddition with N,N′-Cyclic azomethine imines
(Journal of Organometallic Chemistry, 2018-04)
AlCl3-Catalyzed [3 + 2] dipolar cycloaddition of the N,N′-cyclic azomethine imines to the acryloylferrocene enabling access to the series of 5-substituted 6-ferrocenoyl tetrahydropyrazolo [1,2-a]pyrazol-1(5H)-ones. This ...
Synthesis and structural characterizations of novel atropoisomeric ferrocene-containing six-membered cyclic ureas
(Polyhedron, 2020-02)
The stereochemical phenomenon that arises from hindered rotation around bonds in nonplanar molecules is termed the atropoisomerism. During our previous work we noted the presence of this kind of isomerism in 1-aryl-4-fer ...
Electrochemical characterization and estimation of DNA-binding capacity of a series of novel ferrocene derivatives
(Bioelectrochemistry, 2020-04)
The synthesis of a series of methyl 2-alkyl-5-aryl-4-ferrocenoylpyrrolidine-2-carboxylates has been achieved by [3 + 2] dipolar cycloaddition of azomethine ylides to acryloylferrocene. The electrochemical properties of ...
Synthesis, characterization, antioxidant and antimicrobial activity of novel 5-arylidene-2-ferrocenyl-1,3-thiazolidin-4-ones
(Journal of Organometallic Chemistry, 2018-08)
Synthesis of twenty novel 5-arylidene-2-ferrocenyl-1,3-thiazolidin-4-ones has been achieved in good to excellent yields by the Knoevenagel condensation of 2-ferrocenyl-1,3-thiazolidin-4-ones with aromatic aldehydes. The ...
Synthesis of novel multi-functionalized pyrrolidines by [3 + 2] dipolar cycloaddition of azomethine ylides and vinyl ketones
(Monatshefte fuer Chemie/Chemical Monthly, 2019-02)
An efficient and easy synthetic route to substituted pyrrolidine derivatives has been established through [3 + 2] dipolar cycloaddition of vinyl ketones and azomethine ylides. The reactions proceed smoothly, under mild ...
Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones
(Polyhedron, 2018-11)
A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were ...
Synthesis of novel ferrocene-containing 1,3-thiazinan-2-imines: One-pot reaction promoted by ultrasound irradiation
(Tetrahedron Letters, 2018-09)
A simple one-pot synthesis of new ferrocene-containing 1,3-thiazinan-2-imines from 3-arylamino-1-ferrocenylpropan-1-ols and phenyl isothiocyanate has been developed. The key intermediate β-hydroxy thioureas were generated ...